HitPredict

Interactor 1: CAC1A (O00555)
Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Voltage-gated calcium channel subunit alpha Cav2.1)
Gene: CACNA1A

Interactor 2: Q8TAS6 (Q8TAS6)
LAMB1 protein
Gene: LAMB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	21078624
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2506 Hs			1 1083
+	Hs
		132361 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		JAG2_HUMAN (242-583): 1.02e-18: 94.5: 12.71
+	Hs
		132283 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		LAMB1_HUMAN (3-200): 2.86e-17: 89.9: 23.77
+	Hs
		132298 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		NOTC1_HUMAN (278-559): 8.66e-14: 78.8: 12.33
+	Hs
		132274 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		MEGF6_HUMAN (67-276): 3.51e-12: 73.2: 34.38
+	Hs
		132305 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		PGBM_HUMAN (7-120): 5.25e-10: 66.2: 29.92
+	Dm
		422755 CAC1D_DROME (1194-1544): 1.16e-38: 162: 22.79		NOTCH_DROME (4-273): 3.11e-12: 73.4: 11.11
+	Mm
		358687 CAC1C_MOUSE (1126-1515): 2.46e-30: 134: 18.67		LAMB1_MOUSE (4-156): 7.51e-14: 78.8: 24.69