HitPredict

Interactor 1: UVR8 (Q9FN03)
Ultraviolet-B receptor UVR8 (Protein UV-B RESISTANCE 8) (RCC1 domain-containing protein UVR8)
Gene: UVR8

Interactor 2: RUP1 (Q9LTJ6)
WD repeat-containing protein RUP1 (Protein EARLY FLOWERING BY OVEREXPRESSION 1) (Protein REPRESSOR OF UV-B PHOTOMORPHOGENESIS 1)
Gene: RUP1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	25627067, 21041653, 22988111, 24277841
Identification Methods	two hybrid, protein complementation assay, affinity chromatography technology, bimolecular fluorescence complementation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0010224 - response to UV-B
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 440 At			1 385
+	At
		1322580 UVR8_ARATH (1-440): 0: 559: 100.00		RUP2_ARATH (72-384): 2.69e-85: 265: 62.08
+	At
		1324631 UVR8_ARATH (1-440): 0: 559: 100.00		SPA2_ARATH (25-281): 3.55e-26: 112: 16.43
+	At
		794492 UVR8_ARATH (1-440): 0: 559: 100.00		COP1_ARATH (164-383): 3.91e-26: 112: 15.72
+	At
		1277620 UVR8_ARATH (1-440): 0: 559: 100.00		SPA4_ARATH (25-284): 1.19e-25: 110: 17.08
+	At
		1324630 UVR8_ARATH (1-440): 0: 559: 100.00		SPA1_ARATH (29-273): 3.42e-24: 106: 15.29
+	At
		1324626 UVR8_ARATH (1-440): 0: 559: 100.00		SPA3_ARATH (256-384): 4.16e-09: 60.3: 15.22
+	Mm
		1225124 NEK9_MOUSE (9-431): 1.57e-102: 328: 25.11		FBXW7_MOUSE (2-278): 1.1e-61: 212: 13.29
+	Hs
		1281460 HERC5_HUMAN (15-161): 5.6e-15: 79.3: 30.67		FBXW7_HUMAN (2-278): 1.28e-60: 209: 13.29
+	Hs
		319956 HERC2_HUMAN (5-81): 2.41e-10: 65: 28.57		FBXW7_HUMAN (2-278): 1.28e-60: 209: 13.29
+	Hs
		578408 RCC1_HUMAN (240-418): 4.74e-26: 111: 24.04		WDR5_HUMAN (248-383): 4.15e-27: 111: 18.98
+	Hs
		1288357 RCC2_HUMAN (314-418): 6.2e-16: 81.9: 22.43		SNR40_HUMAN (244-384): 2.03e-27: 112: 19.72
+	Hs
		903569 RCC2_HUMAN (314-418): 6.2e-16: 81.9: 22.43		WDR5_HUMAN (248-383): 4.15e-27: 111: 18.98
+	Hs
		1246188 RCC2_HUMAN (314-418): 6.2e-16: 81.9: 22.43		COP1_HUMAN (30-284): 4.71e-24: 106: 15.16
+	Hs
		1246195 HERC5_HUMAN (15-161): 5.6e-15: 79.3: 30.67		COP1_HUMAN (30-284): 4.71e-24: 106: 15.16