HitPredict

Interactor 1: PGPLC (Q9GNK5)
Peptidoglycan-recognition protein LC (Immune response deficient 7 protein)
Gene: PGRP-LC

Interactor 2: PGPLC (Q9GNK5)
Peptidoglycan-recognition protein LC (Immune response deficient 7 protein)
Gene: PGRP-LC

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 15657141, 29045898, 21372849, 37061542, 23749869
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, two hybrid, surface plasmon resonance
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Amidase_2~Amidase_2
Common GO terms GO:0001875 - lipopolysaccharide immune receptor activity
GO:0002920 - regulation of humoral immune response
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0006963 - positive regulation of antibacterial peptide biosynthetic process
and 18 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 520
Dm

1 520
+ Dm
+ Dm
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024