HitPredict

Interactor 1: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Interactor 2: MTCL1 (Q9Y4B5)
Microtubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2)
Gene: MTCL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0007059 - chromosome segregation GO:0008017 - microtubule binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 1905
+	Hs
		1136748 CYTSA_HUMAN (2-331): 7.36e-23: 102: 16.06		MTCL3_HUMAN (7-894): 6.1e-89: 315: 42.06
+	Hs
		1113843 NDEL1_HUMAN (1-345): 1.8e-67: 217: 100.00		GRDN_HUMAN (309-722): 1.56e-14: 81.9: 20.40
+	Hs
		725097 MYH11_HUMAN (2-223): 2.17e-26: 112: 18.92		MYH10_HUMAN (127-797): 1.09e-16: 89: 10.88
+	Hs
		148461 CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32		MYH10_HUMAN (127-797): 1.09e-16: 89: 10.88
+	Hs
		724687 MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57		MYH10_HUMAN (127-797): 1.09e-16: 89: 10.88
+	Hs
		148466 CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32		MYH11_HUMAN (1036-1546): 1.17e-15: 85.9: 8.86
+	Hs
		725095 MYH10_HUMAN (2-228): 6.16e-23: 102: 18.06		MYH10_HUMAN (127-797): 1.09e-16: 89: 10.88
+	Hs
		148359 CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32		DESP_HUMAN (294-843): 6.21e-12: 73.4: 16.70
+	Hs
		148460 CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Hs
		724686 MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Hs
		148841 CTRO_HUMAN (12-211): 2.55e-24: 106: 19.32		PLEC_HUMAN (321-1278): 1.45e-09: 65.7: 16.15
+	Hs
		724873 CYTSA_HUMAN (2-331): 7.36e-23: 102: 16.06		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Hs
		724839 MYH9_HUMAN (2-223): 7.48e-24: 105: 17.57		PLEC_HUMAN (321-1278): 1.45e-09: 65.7: 16.15
+	Hs
		1068649 KIFC1_HUMAN (12-245): 7e-23: 101: 16.24		PLEC_HUMAN (321-1278): 1.45e-09: 65.7: 16.15
+	Hs
		725189 MYH14_HUMAN (2-216): 1.78e-13: 73.5: 19.54		MYH10_HUMAN (127-797): 1.09e-16: 89: 10.88
+	Hs
		724895 MYH14_HUMAN (2-216): 1.78e-13: 73.5: 19.54		MYH9_HUMAN (171-636): 9.75e-11: 69.3: 10.04
+	Hs
		1068614 CTTB2_HUMAN (1-342): 7.57e-11: 65.4: 13.50		PLEC_HUMAN (321-1278): 1.45e-09: 65.7: 16.15