Interactor 1: DERL2 (Q9GZP9)
Derlin-2 (Degradation in endoplasmic reticulum protein 2) (DERtrin-2) (Der1-like protein 2) (F-LAN-1) (F-LANa)
Gene: DERL2

Interactor 2: SE1L1 (Q9UBV2)
Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L)
Gene: SEL1L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.709

The method score is based on:

Property Details
Experiments 22119785, 36045259, 16186509, 23867461, 24366871
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0036503 - ERAD pathway
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 239
Hs

1 794
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024