HitPredict

Interactor 1: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Interactor 2: ATG10 (Q9H0Y0)
Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like)
Gene: ATG10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20562859
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0005829 - cytosol GO:0006914 - autophagy GO:0016236 - macroautophagy
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 125 Hs			1 220
+	Hs
		61902 MP3B2_HUMAN (1-125): 5e-56: 172: 99.20		ATG10_HUMAN (1-220): 4.65e-112: 321: 100.00
+	Hs
		891316 GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47		ATG10_HUMAN (1-220): 4.65e-112: 321: 100.00
+	Hs
		306312 GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30		ATG10_HUMAN (1-220): 4.65e-112: 321: 100.00
+	Hs
		1315801 MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00		ATG10_HUMAN (1-220): 4.65e-112: 321: 100.00
+	Hs
		1328025 GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46		ATG10_HUMAN (1-220): 4.65e-112: 321: 100.00
+	Mm
		1246814 MLP3B_MOUSE (1-125): 1.09e-55: 171: 95.20		ATG10_MOUSE (3-216): 8.99e-107: 307: 80.84
+	At
		1013368 ATG8F_ARATH (3-120): 1.05e-58: 178: 37.29		ATG3_ARATH (34-209): 5.8e-57: 184: 13.26
+	Hs
		1326176 MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Hs
		61904 MP3B2_HUMAN (1-125): 5e-56: 172: 99.20		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Hs
		1330642 MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Mm
		1265087 MLP3A_MOUSE (1-120): 8.21e-55: 168: 82.50		ATG3_MOUSE (54-210): 2.12e-51: 170: 18.63
+	Hs
		891336 GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Hs
		306334 GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Hs
		1315807 MLP3C_HUMAN (1-120): 2.08e-51: 161: 55.00		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Hs
		1328043 GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Ce
		999358 LGG1_CAEEL (6-120): 5.55e-51: 159: 33.04		Q9N369_CAEEL (70-211): 1.12e-42: 147: 23.45
+	Ce
		1095400 LGG2_CAEEL (6-120): 6.06e-45: 144: 58.26		Q9N369_CAEEL (70-211): 1.12e-42: 147: 23.45
+	Pf
		83078 Q8IJK2_PLAF7 (6-120): 2.88e-45: 144: 31.45		C0H519_PLAF7 (88-209): 1.91e-37: 134: 21.60
+	Sc
		745998 ATG8_YEAST (4-120): 5.69e-55: 168: 34.19		ATG3_YEAST (39-209): 1.69e-26: 105: 13.30