Interactor 1: RPA49 (Q9GZS1)
DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53)
Gene: POLR1E

Interactor 2: RRN3 (Q9NYV6)
RNA polymerase I-specific transcription initiation factor RRN3 (Transcription initiation factor IA) (TIF-IA)
Gene: RRN3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 33961781, 19214185
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_I_A49~RRN3
Common GO terms GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006361 - transcription initiation at RNA polymerase I promoter
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 419
Hs

1 651
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024