HitPredict

Interactor 1: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Interactor 2: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	36950384
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016055 - Wnt signaling pathway
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 305 Hs			1 2581
+	Hs
		209485 PLRG1_HUMAN (4-217): 2.47e-43: 156: 22.52		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	Hs
		903535 WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33		CHD8_HUMAN (1-2581): 0: 2318: 100.00
+	Hs
		1018714 NLE1_HUMAN (7-304): 9.15e-91: 279: 21.61		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018633 SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1059779 FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		903234 WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		197011 PRP4_HUMAN (218-304): 3.86e-14: 74.2: 13.68		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1018751 WDR3_HUMAN (6-218): 4.82e-10: 62.4: 25.56		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		1016272 TBL3_HUMAN (151-265): 1.22e-09: 61.2: 28.93		CHD3_HUMAN (385-2065): 0: 1037: 23.37
+	Hs
		658714 FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30		SMCA1_HUMAN (654-1705): 0: 875: 26.13
+	Hs
		658715 SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42		SMCA1_HUMAN (654-1705): 0: 875: 26.13
+	Hs
		197020 PRP4_HUMAN (218-304): 3.86e-14: 74.2: 13.68		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1059943 WDR3_HUMAN (6-218): 4.82e-10: 62.4: 25.56		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		1016277 TBL3_HUMAN (151-265): 1.22e-09: 61.2: 28.93		CHD4_HUMAN (500-2065): 0: 981: 23.88
+	Hs
		151440 FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30		CHD1_HUMAN (530-1808): 0: 828: 27.06
+	Hs
		151443 SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42		CHD1_HUMAN (530-1808): 0: 828: 27.06
+	Hs
		847050 FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30		SMCA4_HUMAN (69-1478): 0: 806: 23.14
+	Hs
		847053 SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42		SMCA4_HUMAN (69-1478): 0: 806: 23.14
+	Hs
		1254435 FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30		CHD6_HUMAN (1354-2489): 1.68e-106: 385: 14.08