Interactor 1: FGF23 (Q9GZV9)
Fibroblast growth factor 23 (FGF-23) (Phosphatonin) (Tumor-derived hypophosphatemia-inducing factor) [Cleaved into: Fibroblast growth factor 23 N-terminal peptide; Fibroblast growth factor 23 C-terminal peptide]
Gene: FGF23

Interactor 2: KLOT (Q9UEF7)
Klotho (EC 3.2.1.31) [Cleaved into: Klotho peptide]
Gene: KL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 27879395
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0008543 - fibroblast growth factor receptor signaling pathway
GO:0055074 - calcium ion homeostasis
GO:0090080 - positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 251
Hs

1 1012
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024