HitPredict

Interactor 1: MKRN2 (Q9H000)
E3 ubiquitin-protein ligase makorin-2 (EC 2.3.2.27) (RING finger protein 62) (RING-type E3 ubiquitin transferase makorin-2)
Gene: MKRN2

Interactor 2: IF2B2 (Q9Y6M1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: IGF2BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 599
+	Hs
		128297 MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		1327000 MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		1355341 MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71		IF2B2_HUMAN (1-599): 1.06e-146: 438: 100.00
+	Hs
		128331 MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		1349160 MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		1023574 MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		1294247 MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Hs
		1345996 MBNL3_HUMAN (2-158): 5.44e-11: 65.8: 20.36		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Dm
		112948 Q9VP20_DROME (28-386): 1.95e-106: 321: 33.70		M9NF14_DROME (4-503): 5.85e-23: 105: 14.89
+	Hs
		904158 MBNL1_HUMAN (1-168): 5.44e-09: 59.6: 13.79		HNRPK_HUMAN (386-596): 5.84e-18: 88.9: 17.09