HitPredict

Interactor 1: RB33B (Q9H082)
Ras-related protein Rab-33B
Gene: RAB33B

Interactor 2: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0000139 - Golgi membrane GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005794 - Golgi apparatus GO:0006891 - intra-Golgi vesicle-mediated transport and 1 others more... GO:0098793 - presynapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 208
+	Zm
		73944 B4FAE1_MAIZE (26-229): 6.15e-89: 262: 36.72		B4FAE1_MAIZE (7-207): 1.43e-90: 265: 34.33
+	Hs
		1327297 RB33B_HUMAN (1-229): 8.59e-90: 265: 100.00		RAB1B_HUMAN (7-206): 1.58e-87: 258: 35.50
+	Hs
		844470 RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		592400 RAB2B_HUMAN (30-226): 8.06e-87: 257: 38.69		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		918846 RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62		RAB1A_HUMAN (1-207): 7.26e-89: 261: 34.30
+	Hs
		895217 RAB2A_HUMAN (29-220): 1.13e-86: 257: 39.18		RAB8B_HUMAN (10-207): 6.35e-89: 261: 38.31
+	Hs
		918916 RAB2B_HUMAN (30-226): 8.06e-87: 257: 38.69		RAB1A_HUMAN (1-207): 7.26e-89: 261: 34.30
+	Hs
		918944 RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62		RAB1B_HUMAN (7-206): 1.58e-87: 258: 35.50
+	Hs
		895264 RAB2A_HUMAN (29-220): 1.13e-86: 257: 39.18		RAB1B_HUMAN (7-206): 1.58e-87: 258: 35.50
+	Mm
		919000 RAB1A_MOUSE (23-229): 3.09e-87: 258: 37.62		RAB1B_MOUSE (7-206): 2.65e-87: 257: 36.50
+	Mm
		877189 RAB8A_MOUSE (26-226): 2.83e-87: 258: 38.54		RAB8B_MOUSE (10-207): 2.14e-85: 252: 38.31
+	Hs
		592648 RAB2A_HUMAN (29-220): 1.13e-86: 257: 39.18		RAB6A_HUMAN (1-208): 1.37e-84: 250: 90.87
+	Hs
		913992 RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		895216 RAB2A_HUMAN (29-220): 1.13e-86: 257: 39.18		RAB1C_HUMAN (7-206): 2.98e-84: 249: 35.00
+	Hs
		918879 RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62		RB11B_HUMAN (7-208): 5.29e-82: 244: 28.91
+	Hs
		895370 RAB2B_HUMAN (30-226): 8.06e-87: 257: 38.69		RAB5B_HUMAN (13-178): 5.66e-49: 160: 45.78
+	Hs
		1205926 RB33B_HUMAN (1-229): 8.59e-90: 265: 100.00		RAB43_HUMAN (14-174): 7.7e-45: 149: 44.44
+	Hs
		895026 RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89
+	Hs
		895204 RAB2B_HUMAN (30-226): 8.06e-87: 257: 38.69		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89