HitPredict

Interactor 1: TOLIP (Q9H0E2)
Toll-interacting protein
Gene: TOLLIP

Interactor 2: GGA3 (Q9NZ52)
ADP-ribosylation factor-binding protein GGA3 (Golgi-localized, gamma ear-containing, ARF-binding protein 3)
Gene: GGA3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15047686
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032991 - protein-containing complex GO:0043130 - ubiquitin binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 274 Hs			1 723
+	Hs
		1327604 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		GGA1_HUMAN (2-723): 1.09e-91: 301: 39.78
+	Hs
		1173027 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		TM1L2_HUMAN (7-511): 5.58e-88: 287: 21.58
+	Hs
		241171 Q6FIE9_HUMAN (1-274): 6.84e-178: 492: 100.00		TOM1_HUMAN (7-402): 8.19e-85: 278: 22.76
+	Hs
		241195 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		TOM1_HUMAN (7-402): 8.19e-85: 278: 22.76
+	Hs
		1270615 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		STAM1_HUMAN (1-522): 4.18e-75: 254: 17.10
+	Rn
		58593 TOLIP_RAT (1-273): 9.9e-166: 461: 93.41		Q5XI21_RAT (7-402): 1.04e-80: 267: 24.70
+	Mm
		292211 TOLIP_MOUSE (1-273): 2.66e-165: 460: 93.04		TOM1_MOUSE (7-460): 2.12e-80: 266: 20.92
+	Hs
		272820 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		TM1L1_HUMAN (6-473): 8.9e-63: 219: 16.50
+	Hs
		160182 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		HGS_HUMAN (8-709): 5.07e-58: 212: 13.37
+	Hs
		1327603 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		GGA2_HUMAN (456-721): 1.1e-25: 114: 34.83