HitPredict

Interactor 1: UBP44 (Q9H0E7)
Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.4.19.12) (Deubiquitinating enzyme 44) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44)
Gene: USP44

Interactor 2: TBL2 (Q9Y4P3)
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)
Gene: TBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.595

Property	Details
Experiments	19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UCH~WD40
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 712 Hs			1 447
+	Hs
		1318177 UBP44_HUMAN (1-712): 0: 597: 100.00		TBL1R_HUMAN (3-260): 1.52e-55: 193: 11.40
+	Hs
		245635 UBP44_HUMAN (1-712): 0: 597: 100.00		TBL1X_HUMAN (3-260): 4.69e-45: 166: 13.36
+	Hs
		903505 UBP44_HUMAN (1-712): 0: 597: 100.00		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		1016340 UBP36_HUMAN (295-710): 3.42e-91: 309: 20.71		TBL3_HUMAN (12-447): 1.29e-58: 207: 13.88
+	Hs
		1288312 UBP42_HUMAN (226-710): 3.3e-95: 323: 19.96		SNR40_HUMAN (258-447): 3.49e-34: 132: 13.02
+	Hs
		1288358 UBP36_HUMAN (295-710): 3.42e-91: 309: 20.71		SNR40_HUMAN (258-447): 3.49e-34: 132: 13.02
+	Hs
		267805 UBP22_HUMAN (305-681): 7.04e-101: 321: 25.69		TAF5L_HUMAN (76-247): 1.76e-26: 114: 15.76
+	Hs
		903571 UBP36_HUMAN (295-710): 3.42e-91: 309: 20.71		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Hs
		64195 UBP27_HUMAN (288-689): 1.35e-100: 317: 24.71		TAF5L_HUMAN (76-247): 1.76e-26: 114: 15.76
+	Hs
		267775 UBP51_HUMAN (307-682): 2.61e-94: 309: 26.32		TAF5L_HUMAN (76-247): 1.76e-26: 114: 15.76
+	Hs
		1346960 UBP36_HUMAN (295-710): 3.42e-91: 309: 20.71		NLE1_HUMAN (356-445): 8.01e-19: 90.6: 15.56
+	Dm
		186227 Q9VDD8_DROME (141-676): 7.27e-101: 331: 21.16		GBLP_DROME (12-167): 8.97e-09: 58.8: 13.04
+	Sc
		744649 UBP8_YEAST (243-679): 6.63e-84: 275: 26.24		TAF5_YEAST (269-419): 6.91e-11: 66.4: 17.61
+	Hs
		1200165 UBP48_HUMAN (255-657): 6.02e-20: 97.1: 24.69		SNR40_HUMAN (258-447): 3.49e-34: 132: 13.02
+	Mm
		932618 UBP48_MOUSE (255-693): 3.01e-21: 101: 24.25		RACK1_MOUSE (266-445): 3.22e-20: 92.7: 16.30