Interactor 1: SHRPN (Q9H0F6)
Sharpin (Shank-associated RH domain-interacting protein) (Shank-interacting protein-like 1) (hSIPL1)
Gene: SHARPIN

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.55 0.613

The method score is based on:

Property Details
Experiments 26670046, 27591049, 31067453
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0010803 - regulation of tumor necrosis factor-mediated signaling pathway
GO:0050728 - negative regulation of inflammatory response
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024