Interactor 1: RGAP1 (Q9H0H5)
Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4)
Gene: RACGAP1

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 25486482, 31586073, 18201571, 19468300, 19468302, 22750944, 25068414
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid, isothermal titration calorimetry
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~RhoGEF
Common GO terms GO:0000281 - mitotic cytokinesis
GO:0005096 - GTPase activator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 7 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 632
Hs

1 914
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs

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Last updated: 15 Jul 2024