HitPredict

Interactor 1: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Interactor 2: RETR1 (Q9H6L5)
Reticulophagy regulator 1 (Reticulophagy receptor 1)
Gene: RETREG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.642

Property	Details
Experiments	31006538, 36949045, 26040720
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 497
+	Hs
		891323 GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		306320 GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Mm
		1257559 MLP3B_MOUSE (2-116): 3.03e-44: 141: 31.62		RETR1_MOUSE (1-497): 0: 767: 87.32
+	Hs
		1330625 MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1326146 MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		61903 MP3B2_HUMAN (2-116): 6.71e-43: 138: 30.77		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		891208 GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202377 GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		306223 GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202382 MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202374 MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1240861 GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		306234 GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		1240862 MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		1240860 MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57