HitPredict

Interactor 1: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Interactor 2: ATG4B (Q9Y4P1)
Cysteine protease ATG4B (EC 3.4.22.-) (AUT-like 1 cysteine endopeptidase) (Autophagy-related cysteine endopeptidase 1) (Autophagin-1) (Autophagy-related protein 4 homolog B) (HsAPG4B) (hAPG4B)
Gene: ATG4B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 28287329, 32296183, 20562859, 19549685, 33961781, 35271311, 16704426, unassigned1304
Identification Methods pull down, x-ray crystallography, two hybrid, affinity chromatography technology, enzymatic study, protease assay, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type direct interaction, association, physical association, cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains ATG8~Peptidase_C54
Common GO terms GO:0000045 - autophagosome assembly
GO:0000421 - autophagosome membrane
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 117
Hs

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Last updated: 15 Jul 2024