HitPredict

Interactor 1: CCDC8 (Q9H0W5)
Coiled-coil domain-containing protein 8
Gene: CCDC8

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24711643
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 538 Hs			1 7388
+	Hs
		885311 CCDC8_HUMAN (1-538): 0: 665: 100.00		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		1068659 CCDC8_HUMAN (1-538): 0: 665: 100.00		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		551833 CCDC8_HUMAN (1-538): 0: 665: 100.00		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		974143 CCDC8_HUMAN (1-538): 0: 665: 100.00		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		164662 CCDC8_HUMAN (1-538): 0: 665: 100.00		SPTN2_HUMAN (3436-4815): 1.06e-11: 74.8: 9.59
+	Hs
		809165 CCDC8_HUMAN (1-538): 0: 665: 100.00		UTRN_HUMAN (428-1437): 8.81e-11: 71.9: 13.98
+	Hs
		1059265 CCDC8_HUMAN (1-538): 0: 665: 100.00		GOGB1_HUMAN (6684-7219): 2.29e-10: 70.5: 9.23
+	Hs
		1068628 MOAP1_HUMAN (1-97): 2.67e-26: 111: 25.77		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13