Interactor 1: ING2 (Q9H160)
Inhibitor of growth protein 2 (Inhibitor of growth 1-like protein) (ING1Lp) (p32) (p33ING2)
Gene: ING2

Interactor 2: SMUF1 (Q9HCE7)
E3 ubiquitin-protein ligase SMURF1 (hSMURF1) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF1) (SMAD ubiquitination regulatory factor 1) (SMAD-specific E3 ubiquitin-protein ligase 1)
Gene: SMURF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.59 0.60 0.596

The method score is based on:

Property Details
Experiments 20621832
Identification Methods enzymatic study, affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 280
Hs

1 757
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024