Interactor 1: APC1 (Q9H1A4)
Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)
Gene: ANAPC1

Interactor 2: CDC23 (Q9UJX2)
Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)
Gene: CDC23

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.687

The method score is based on:

Property Details
Experiments 26496610, 35271311, 11076961, 20360068
Identification Methods affinity chromatography technology, biochemical, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007091 - metaphase/anaphase transition of mitotic cell cycle
GO:0007346 - regulation of mitotic cell cycle
and 4 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1944
Hs

1 597
+ Hs
+ Hs
+ Hs
+ At
+ At
+ At
+ Sp
+ Sp
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024