HitPredict

Interactor 1: EPN3 (Q9H201)
Epsin-3 (EPS-15-interacting protein 3)
Gene: EPN3

Interactor 2: EHD1 (Q9H4M9)
EH domain-containing protein 1 (PAST homolog 1) (hPAST1) (Testilin)
Gene: EHD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21115825
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 632 Hs			1 534
+	Mm
		1265097 EPN3_MOUSE (1-632): 7.74e-75: 253: 82.74		EHD1_MOUSE (1-534): 0: 823: 99.44
+	Hs
		1328941 EPN3_HUMAN (1-632): 1.32e-92: 300: 100.00		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Mm
		1206518 EPN3_MOUSE (1-632): 7.74e-75: 253: 82.74		EHD2_MOUSE (1-534): 0: 777: 70.87
+	Mm
		1194352 EPN1_MOUSE (1-592): 7.73e-58: 206: 36.72		EHD1_MOUSE (1-534): 0: 823: 99.44
+	Hs
		1331796 EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64		EHD1_HUMAN (1-534): 0: 822: 100.00
+	Ce
		1259347 Q9BI72_CAEEL (1-526): 4.75e-64: 220: 30.25		Q8WSP1_CAEEL (1-534): 0: 777: 66.85
+	Mm
		1194350 EPN1_MOUSE (1-592): 7.73e-58: 206: 36.72		EHD2_MOUSE (1-534): 0: 777: 70.87
+	Hs
		1349324 EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64		EHD2_HUMAN (1-534): 0: 776: 70.50
+	Hs
		1223707 ENTD1_HUMAN (5-327): 1.08e-78: 263: 36.22		REPS1_HUMAN (372-527): 2e-35: 143: 28.66
+	Hs
		1057081 EPN4_HUMAN (3-628): 4.33e-76: 256: 21.77		REPS1_HUMAN (372-527): 2e-35: 143: 28.66
+	Hs
		1244792 EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64		REPS2_HUMAN (315-527): 1.56e-47: 177: 22.79
+	Hs
		787969 EPN3_HUMAN (1-632): 1.32e-92: 300: 100.00		EPS15_HUMAN (446-528): 4.73e-13: 73.9: 34.52
+	Hs
		307533 EPN2_HUMAN (1-632): 5.11e-66: 229: 33.54		ITSN1_HUMAN (426-527): 3.14e-29: 125: 37.26
+	Hs
		787913 EPN4_HUMAN (3-628): 4.33e-76: 256: 21.77		EPS15_HUMAN (446-528): 4.73e-13: 73.9: 34.52
+	Mm
		1194353 EPN1_MOUSE (1-592): 7.73e-58: 206: 36.72		ITSN1_MOUSE (426-527): 9.71e-29: 123: 38.24
+	Sc
		692257 ENT1_YEAST (3-211): 2.58e-63: 217: 36.36		PAN1_YEAST (332-521): 4.24e-20: 96.7: 21.47
+	Sc
		692249 ENT2_YEAST (3-213): 5.86e-52: 191: 31.28		PAN1_YEAST (332-521): 4.24e-20: 96.7: 21.47
+	Dm
		91160 Q7KU90_DROME (1-622): 4.26e-51: 191: 26.90		E3CTP7_DROME (434-531): 2.68e-17: 87.3: 34.00
+	Hs
		787997 EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64		EPS15_HUMAN (446-528): 4.73e-13: 73.9: 34.52
+	Hs
		1353935 EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64		EP15R_HUMAN (448-530): 3.14e-09: 61.6: 32.14