HitPredict

Interactor 1: EPN3 (Q9H201)
Epsin-3 (EPS-15-interacting protein 3)
Gene: EPN3

Interactor 2: EHD2 (Q9NZN4)
EH domain-containing protein 2 (PAST homolog 2)
Gene: EHD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21115825
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 632 Hs			1 543
+	Hs
		1328938 EPN3_HUMAN (1-632): 1.32e-92: 300: 100.00		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Mm
		1206518 EPN3_MOUSE (1-632): 7.74e-75: 253: 82.74		EHD2_MOUSE (1-543): 0: 837: 96.69
+	Mm
		1265097 EPN3_MOUSE (1-632): 7.74e-75: 253: 82.74		EHD1_MOUSE (1-538): 0: 819: 70.26
+	Mm
		1194350 EPN1_MOUSE (1-592): 7.73e-58: 206: 36.72		EHD2_MOUSE (1-543): 0: 837: 96.69
+	Hs
		1349324 EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64		EHD2_HUMAN (1-543): 0: 838: 100.00
+	Mm
		1194352 EPN1_MOUSE (1-592): 7.73e-58: 206: 36.72		EHD1_MOUSE (1-538): 0: 819: 70.26
+	Hs
		1331796 EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Ce
		1259347 Q9BI72_CAEEL (1-526): 4.75e-64: 220: 30.25		Q8WSP1_CAEEL (1-540): 0: 791: 60.15
+	Hs
		787969 EPN3_HUMAN (1-632): 1.32e-92: 300: 100.00		EPS15_HUMAN (451-541): 3.38e-13: 74.7: 26.09
+	Hs
		307533 EPN2_HUMAN (1-632): 5.11e-66: 229: 33.54		ITSN1_HUMAN (444-532): 7.23e-28: 120: 36.67
+	Hs
		1244792 EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64		REPS2_HUMAN (398-532): 1.26e-34: 140: 31.39
+	Hs
		787913 EPN4_HUMAN (3-628): 4.33e-76: 256: 21.77		EPS15_HUMAN (451-541): 3.38e-13: 74.7: 26.09
+	Mm
		1194353 EPN1_MOUSE (1-592): 7.73e-58: 206: 36.72		ITSN1_MOUSE (444-532): 3.01e-27: 118: 36.67
+	Sc
		692257 ENT1_YEAST (3-211): 2.58e-63: 217: 36.36		PAN1_YEAST (381-528): 2.88e-17: 87.8: 23.49
+	Hs
		787920 EPS15_HUMAN (38-569): 4e-46: 177: 10.26		ITSN1_HUMAN (444-532): 7.23e-28: 120: 36.67
+	Sc
		692249 ENT2_YEAST (3-213): 5.86e-52: 191: 31.28		PAN1_YEAST (381-528): 2.88e-17: 87.8: 23.49
+	Hs
		787997 EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64		EPS15_HUMAN (451-541): 3.38e-13: 74.7: 26.09
+	Hs
		1353935 EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64		EP15R_HUMAN (453-541): 3.2e-09: 61.6: 27.78
+	Hs
		61732 EPS15_HUMAN (38-569): 4e-46: 177: 10.26		A6H8W8_HUMAN (444-533): 3.84e-14: 77.8: 39.56
+	Hs
		787860 EPS15_HUMAN (38-569): 4e-46: 177: 10.26		EPS15_HUMAN (451-541): 3.38e-13: 74.7: 26.09