HitPredict

Interactor 1: P2Y12 (Q9H244)
P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)
Gene: P2RY12

Interactor 2: TM9S3 (Q9HD45)
Transmembrane 9 superfamily member 3 (EP70-P-iso) (SM-11044-binding protein)
Gene: TM9SF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 342 Hs			1 589
+	Hs
		782477 P2RY2_HUMAN (17-304): 1.23e-71: 228: 24.22		TM9S3_HUMAN (1-589): 0: 775: 100.00
+	Hs
		429132 ADRB2_HUMAN (4-337): 2.52e-67: 219: 16.44		TM9S3_HUMAN (1-589): 0: 775: 100.00
+	Hs
		781105 OPRX_HUMAN (13-330): 8.68e-64: 208: 21.56		TM9S3_HUMAN (1-589): 0: 775: 100.00
+	Hs
		814594 P2RY1_HUMAN (28-309): 2.91e-19: 89.4: 24.40		TM9S3_HUMAN (1-589): 0: 775: 100.00
+	Hs
		782450 P2RY2_HUMAN (17-304): 1.23e-71: 228: 24.22		TM9S4_HUMAN (35-589): 0: 623: 33.49
+	Hs
		895693 CXCR4_HUMAN (18-330): 1.17e-71: 228: 22.54		TM9S4_HUMAN (35-589): 0: 623: 33.49
+	Hs
		723364 APJ_HUMAN (1-340): 9.92e-70: 224: 22.16		TM9S4_HUMAN (35-589): 0: 623: 33.49
+	Hs
		175562 OPRX_HUMAN (13-330): 8.68e-64: 208: 21.56		TM9S1_HUMAN (17-589): 0: 626: 33.28
+	Hs
		175559 PTAFR_HUMAN (11-309): 7.63e-37: 137: 32.57		TM9S1_HUMAN (17-589): 0: 626: 33.28
+	Hs
		626791 PTAFR_HUMAN (11-309): 7.63e-37: 137: 32.57		TM9S4_HUMAN (35-589): 0: 623: 33.49