HitPredict

Interactor 1: IL25 (Q9H293)
Interleukin-25 (IL-25) (Interleukin-17E) (IL-17E)
Gene: IL25

Interactor 2: I17RB (Q9NRM6)
Interleukin-17 receptor B (IL-17 receptor B) (IL-17RB) (Cytokine receptor-like 4) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Interleukin-17B receptor) (IL-17B receptor)
Gene: IL17RB

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.806

Property	Details
Experiments	11058597, 19838198
Identification Methods	pull down, fluorescence-activated cell sorting, surface plasmon resonance
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	IL17~IL17R_fnIII_D1, IL17~IL17R_fnIII_D2
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 177 Hs			1 502
+	Mm
		1257598 IL25_MOUSE (19-177): 1.14e-74: 223: 76.05		I17RB_MOUSE (1-502): 0: 724: 74.55
+	Hs
		1290938 IL25_HUMAN (1-177): 1.58e-92: 268: 100.00		I17RA_HUMAN (13-470): 0: 592: 24.50
+	Hs
		1344942 IL17B_HUMAN (83-171): 6.81e-26: 99.1: 29.21		I17RB_HUMAN (12-502): 0: 734: 100.00
+	Hs
		1290925 IL17F_HUMAN (72-175): 1.01e-38: 131: 29.81		I17RA_HUMAN (13-470): 0: 592: 24.50
+	Hs
		1083093 IL17_HUMAN (67-175): 1.23e-37: 128: 28.18		I17RA_HUMAN (13-470): 0: 592: 24.50
+	Mm
		1141896 IL17C_MOUSE (42-174): 3.75e-37: 128: 31.82		I17RA_MOUSE (14-470): 0: 566: 25.05
+	Mm
		1141892 IL17F_MOUSE (72-175): 3.85e-37: 127: 28.85		I17RA_MOUSE (14-470): 0: 566: 25.05
+	Mm
		1141891 IL17_MOUSE (70-175): 1.31e-35: 123: 25.00		I17RA_MOUSE (14-470): 0: 566: 25.05