HitPredict

Interactor 1: TNKS2 (Q9H2K2)
Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (Protein poly-ADP-ribosyltransferase tankyrase-2) (EC 2.4.2.-) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-2) (TANK2) (Tankyrase-like protein) (Tankyrase-related protein)
Gene: TNKS2

Interactor 2: TNKS2 (Q9H2K2)
Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (Protein poly-ADP-ribosyltransferase tankyrase-2) (EC 2.4.2.-) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-2) (TANK2) (Tankyrase-like protein) (Tankyrase-related protein)
Gene: TNKS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 25547115
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank, Ank~Ank_2, Ank~Ank_3, Ank~Ank_4, Ank_2~Ank_2, Ank_2~Ank_3, Ank_2~Ank_4, Ank_3~Ank_4, Ank_4~Ank_4, PARP~PARP, SAM_2~SAM_2
Common GO terms GO:0000139 - Golgi membrane
GO:0000209 - protein polyubiquitination
GO:0000242 - pericentriolar material
GO:0000781 - chromosome, telomeric region
GO:0003950 - NAD+ ADP-ribosyltransferase activity
and 17 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1166
Hs

1 1166
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+ Rn
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+ Ce

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Last updated: 15 Jul 2024