HitPredict

Interactor 1: TNKS2 (Q9H2K2)
Poly [ADP-ribose] polymerase tankyrase-2 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 6) (ARTD6) (Poly [ADP-ribose] polymerase 5B) (Protein poly-ADP-ribosyltransferase tankyrase-2) (EC 2.4.2.-) (TNKS-2) (TRF1-interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase II) (Tankyrase-2) (TANK2) (Tankyrase-like protein) (Tankyrase-related protein)
Gene: TNKS2

Interactor 2: LCAP (Q9UIQ6)
Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form]
Gene: LNPEP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	10988299, 12080061, 11802774, 22153077
Identification Methods	affinity chromatography technology, pull down, two hybrid, fluorescence polarization spectroscopy
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 1166 Hs			1 1025
+	Hs
		310104 TNKS1_HUMAN (2-335): 1.11e-73: 270: 35.95		LCAP_HUMAN (1-1025): 0: 1233: 100.00
+	Hs
		1350522 ANFY1_HUMAN (303-1098): 3.92e-70: 258: 14.98		LCAP_HUMAN (1-1025): 0: 1233: 100.00