HitPredict

Interactor 1: KLK15 (Q9H2R5)
Kallikrein-15 (EC 3.4.21.-) (ACO protease)
Gene: KLK15

Interactor 2: TMED5 (Q9Y3A6)
Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2) (p28)
Gene: TMED5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 256 Hs			1 229
+	Hs
		884433 TMPS3_HUMAN (4-256): 1.1e-101: 305: 30.45		TMED7_HUMAN (28-229): 2.01e-65: 203: 32.02
+	Hs
		1198231 TM11B_HUMAN (12-252): 2.35e-92: 279: 33.33		TMED7_HUMAN (28-229): 2.01e-65: 203: 32.02
+	Hs
		1034817 KLK5_HUMAN (13-256): 5.32e-98: 290: 41.46		TMED1_HUMAN (17-229): 7.15e-59: 187: 57.01
+	Mm
		372466 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED5_MOUSE (1-229): 1.9e-79: 239: 89.96
+	Mm
		88384 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		D3YZZ5_MOUSE (31-229): 3.88e-64: 200: 32.50
+	Mm
		371886 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED1_MOUSE (23-229): 1.68e-60: 191: 56.73
+	Mm
		372229 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED4_MOUSE (33-225): 2.21e-60: 191: 20.98
+	Mm
		372017 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED3_MOUSE (30-227): 3.76e-60: 190: 29.65
+	Mm
		372367 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED9_MOUSE (32-225): 1.35e-59: 189: 21.85
+	Mm
		372665 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMED2_MOUSE (34-225): 2.17e-60: 189: 24.87
+	Mm
		372505 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		TMEDA_MOUSE (26-225): 2.83e-53: 172: 17.96