HitPredict

Interactor 1: KLK15 (Q9H2R5)
Kallikrein-15 (EC 3.4.21.-) (ACO protease)
Gene: KLK15

Interactor 2: LOXL2 (Q9Y4K0)
Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14)
Gene: LOXL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 256 Hs			1 774
+	Hs
		1354459 KLK11_HUMAN (19-256): 3.18e-107: 312: 50.41		LOXL2_HUMAN (1-774): 0: 1082: 100.00
+	Hs
		1377525 KLK5_HUMAN (13-256): 5.32e-98: 290: 41.46		LOXL2_HUMAN (1-774): 0: 1082: 100.00
+	Mm
		371673 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		LOXL2_MOUSE (1-774): 0: 1063: 86.10
+	Hs
		1271938 KLK6_HUMAN (1-255): 1.16e-108: 315: 43.14		LOXL4_HUMAN (6-438): 6.86e-62: 223: 21.49
+	Mm
		371579 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		LYOX_MOUSE (548-748): 8.65e-103: 324: 49.75
+	Mm
		371808 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		LOXL1_MOUSE (548-748): 7.78e-99: 320: 48.77
+	Mm
		372702 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		LOXL3_MOUSE (6-438): 1.1e-59: 217: 22.20
+	Mm
		372346 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		LOXL4_MOUSE (6-438): 4.45e-56: 207: 22.77
+	Hs
		198481 KLK10_HUMAN (25-256): 3.92e-60: 192: 41.67		DMBT1_HUMAN (427-545): 5.56e-29: 127: 35.29
+	Mm
		371831 CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40		LG3BP_MOUSE (183-302): 3.4e-30: 128: 22.50