HitPredict

Interactor 1: IKZF4 (Q9H2S9)
Zinc finger protein Eos (Ikaros family zinc finger protein 4)
Gene: IKZF4

Interactor 2: IKZF5 (Q9H5V7)
Zinc finger protein Pegasus (Ikaros family zinc finger protein 5)
Gene: IKZF5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 0.60 0.674

The method score is based on:

Property Details
Experiments 10978333, 28514442, 33961781
Identification Methods pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008270 - zinc ion binding
and 2 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 585
Hs

1 419
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024