Interactor 1: HIPK2 (Q9H2X6)
Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)
Gene: HIPK2

Interactor 2: P63 (Q9H3D4)
Tumor protein 63 (p63) (Chronic ulcerative stomatitis protein) (CUSP) (Keratinocyte transcription factor KET) (Transformation-related protein 63) (TP63) (Tumor protein p73-like) (p73L) (p40) (p51)
Gene: TP63

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.594

The method score is based on:

Property Details
Experiments 11925430, 21602882
Identification Methods two hybrid, protein kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0042771 - intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1198
Hs

1 680
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024