Interactor 1: TPK1 (Q9H3S4)
Thiamin pyrophosphokinase 1 (hTPK1) (EC 2.7.6.2) (Placental protein 20) (PP20) (Thiamine pyrophosphokinase 1)
Gene: TPK1
Interactor 2: TPK1 (Q9H3S4)
Thiamin pyrophosphokinase 1 (hTPK1) (EC 2.7.6.2) (Placental protein 20) (PP20) (Thiamine pyrophosphokinase 1)
Gene: TPK1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.918 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29892012, 32296183, 25502805, 31515488, unassigned1304 |
| Identification Methods | two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | TPK_B1_binding~TPK_B1_binding, TPK_B1_binding~TPK_catalytic, TPK_catalytic~TPK_catalytic |
| Common GO terms | GO:0004788 - thiamine diphosphokinase activity GO:0005524 - ATP binding GO:0005829 - cytosol GO:0006772 - thiamine metabolic process GO:0009229 - thiamine diphosphate biosynthetic process and 4 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
