HitPredict

Interactor 1: DNJC5 (Q9H3Z4)
DnaJ homolog subfamily C member 5 (Ceroid-lipofuscinosis neuronal protein 4) (Cysteine string protein) (CSP)
Gene: DNAJC5

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33957083, 19098309
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 303
+	Hs
		1354630 DNJ5B_HUMAN (1-195): 4.2e-68: 208: 68.21		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1290536 DNJA3_HUMAN (6-117): 2.03e-42: 149: 31.93		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		279360 DNJB5_HUMAN (13-108): 7.56e-39: 137: 38.10		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		636530 DNJB2_HUMAN (15-117): 6.32e-39: 137: 35.25		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1354291 DJB11_HUMAN (12-95): 2.85e-37: 134: 44.05		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1245931 DNJB8_HUMAN (15-112): 2.66e-37: 130: 36.36		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		213643 DNJC5_HUMAN (1-198): 5.05e-73: 220: 100.00		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Mm
		893843 DNJC5_MOUSE (1-198): 2.75e-72: 218: 99.50		SGTA_MOUSE (4-140): 2.54e-32: 123: 28.47
+	Hs
		258247 DNJB6_HUMAN (17-79): 1.09e-20: 89.4: 60.94		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Mm
		1194854 DNJA3_MOUSE (6-117): 3.71e-41: 146: 32.77		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Mm
		1194849 DJB11_MOUSE (12-95): 2.2e-39: 139: 44.05		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Mm
		222727 DNJB6_MOUSE (15-109): 8.61e-39: 138: 42.06		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Mm
		1194908 DNJB4_MOUSE (13-85): 9.59e-38: 134: 54.80		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22