HitPredict

Interactor 1: MLP3A (Q9H492)
Microtubule-associated proteins 1A/1B light chain 3A (Autophagy-related protein LC3 A) (Autophagy-related ubiquitin-like modifier LC3 A) (MAP1 light chain 3-like protein 1) (MAP1A/MAP1B light chain 3 A) (MAP1A/MAP1B LC3 A) (Microtubule-associated protein 1 light chain 3 alpha)
Gene: MAP1LC3A

Interactor 2: RETR1 (Q9H6L5)
Reticulophagy regulator 1 (Reticulophagy receptor 1)
Gene: RETREG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.585

Property	Details
Experiments	31006538, 36952345, 26040720
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 121 Hs			1 497
+	Mm
		1257559 MLP3B_MOUSE (1-120): 3.16e-52: 162: 82.50		RETR1_MOUSE (1-497): 0: 767: 87.32
+	Hs
		891323 GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1326146 MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		306320 GBRAP_HUMAN (7-121): 2.99e-52: 161: 30.44		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		61903 MP3B2_HUMAN (1-121): 4.06e-51: 159: 80.99		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1328030 GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1202382 MLP3A_HUMAN (1-121): 4.19e-54: 167: 100.00		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		891208 GBRL2_HUMAN (7-121): 5.54e-54: 166: 41.74		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202374 MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		306223 GBRAP_HUMAN (7-121): 2.99e-52: 161: 30.44		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202377 GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1240862 MLP3A_HUMAN (1-121): 4.19e-54: 167: 100.00		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		1240860 MLP3B_HUMAN (1-121): 6.65e-52: 161: 81.82		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		306234 GBRAP_HUMAN (7-121): 2.99e-52: 161: 30.44		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		1240861 GBRL1_HUMAN (3-120): 5.97e-51: 158: 33.05		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57