Interactor 1: WNK1 (Q9H4A3)
Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1)
Gene: WNK1

Interactor 2: WNK1 (Q9H4A3)
Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1)
Gene: WNK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 20936779
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains OSR1_C~Pkinase, Pkinase~Pkinase
Common GO terms GO:0002028 - regulation of sodium ion transport
GO:0003084 - positive regulation of systemic arterial blood pressure
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
and 51 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 2382
Hs

1 2382
+ Hs
+ Hs
+ Hs
+ Os
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024