Interactor 1: WNK1 (Q9H4A3)
Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1)
Gene: WNK1

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31091453
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0090263 - positive regulation of canonical Wnt signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2382
Hs

1 779
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024