HitPredict - High confidence protein-protein interactions

Method score	Annotation score	Interaction score
0.82	1.00	0.908

Property	Details
Experiments	30471916, 29426904, 36966392, 37099423, 30356214
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Mab-21~Mab-21, Mab-21~Mab-21_C, Mab-21_C~Mab-21_C
Common GO terms	GO:0002218 - activation of innate immune response GO:0002221 - pattern recognition receptor signaling pathway GO:0002230 - positive regulation of defense response to virus by host GO:0002637 - regulation of immunoglobulin production GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway and 34 others more... GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0003690 - double-stranded DNA binding GO:0005524 - ATP binding GO:0005525 - GTP binding GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006281 - DNA repair GO:0006974 - DNA damage response GO:0008340 - determination of adult lifespan GO:0016604 - nuclear body GO:0019933 - cAMP-mediated signaling GO:0019934 - cGMP-mediated signaling GO:0031491 - nucleosome binding GO:0032481 - positive regulation of type I interferon production GO:0035861 - site of double-strand break GO:0038001 - paracrine signaling GO:0042803 - protein homodimerization activity GO:0045087 - innate immune response GO:0046872 - metal ion binding GO:0050863 - regulation of T cell activation GO:0051607 - defense response to virus GO:0061501 - 2',3'-cyclic GMP-AMP synthase activity GO:0071360 - cellular response to exogenous dsRNA GO:0140693 - molecular condensate scaffold activity GO:0140896 - cGAS/STING signaling pathway GO:0160004 - poly-ADP-D-ribose modification-dependent protein binding GO:0160049 - negative regulation of cGAS/STING signaling pathway GO:2000042 - negative regulation of double-strand break repair via homologous recombination GO:2000774 - positive regulation of cellular senescence
Homologous interactions	3