HitPredict

Interactor 1: Q9H4D1 (Q9H4D1)
Protein kinase
Gene: dik

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.710

Property	Details
Experiments	26091241, 26972000, 29435596, 33961781, 35914814
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 784 Hs			1 605
+	Hs
		1302645 Q96T11_HUMAN (1-784): 0: 705: 99.49		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		883676 RIPK4_HUMAN (1-784): 0: 693: 93.99		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1330876 Q9H4D1_HUMAN (1-784): 0: 712: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1302644 Q96T11_HUMAN (1-784): 0: 705: 99.49		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		72802 RIPK4_HUMAN (1-784): 0: 693: 93.99		B4DH70_HUMAN (98-605): 6.62e-144: 428: 85.63
+	Hs
		883666 RIPK4_HUMAN (1-784): 0: 693: 93.99		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1163035 Q9H4D1_HUMAN (1-784): 0: 712: 100.00		TRAF7_HUMAN (416-589): 7.75e-29: 123: 27.12
+	Hs
		883544 RIPK4_HUMAN (1-784): 0: 693: 93.99		TRAF7_HUMAN (416-589): 7.75e-29: 123: 27.12
+	Hs
		862124 DAPK1_HUMAN (464-783): 4.07e-81: 286: 25.39		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1219809 ANKH1_HUMAN (299-603): 4.92e-46: 180: 18.63		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		166894 ANR28_HUMAN (252-524): 4.08e-20: 98: 18.51		LIS1_HUMAN (174-494): 8.99e-74: 243: 21.37
+	Hs
		903354 ANKH1_HUMAN (299-603): 4.92e-46: 180: 18.63		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33