HitPredict

Interactor 1: RHOJ (Q9H4E5)
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Gene: RHOJ

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 214 Hs			1 761
+	Hs
		894610 CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78		GIT1_HUMAN (1-761): 1.3e-176: 527: 100.00
+	Hs
		925751 RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51		GIT1_HUMAN (1-761): 1.3e-176: 527: 100.00
+	Hs
		894000 CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78		GIT2_HUMAN (1-758): 2.93e-147: 451: 64.39
+	Gg
		1154344 Q6LC82_CHICK (22-214): 4.7e-82: 243: 57.51		Q9DG15_CHICK (1-761): 2.03e-155: 471: 85.41
+	Hs
		1050152 RHOJ_HUMAN (1-214): 2.19e-84: 250: 100.00		GIT2_HUMAN (1-758): 2.93e-147: 451: 64.39
+	Hs
		925274 RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51		GIT2_HUMAN (1-758): 2.93e-147: 451: 64.39
+	Hs
		894593 CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78		AGAP1_HUMAN (2-223): 4.13e-57: 211: 32.89
+	Hs
		925724 RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51		ASAP1_HUMAN (2-606): 1.67e-61: 226: 17.06
+	Hs
		894348 CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78		AGAP2_HUMAN (2-223): 3.67e-52: 198: 32.00
+	Hs
		894263 CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78		ARAP2_HUMAN (7-223): 6.18e-51: 195: 27.15
+	Mm
		892722 CDC42_MOUSE (20-204): 2.24e-92: 270: 63.78		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Hs
		894325 CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78		ARAP1_HUMAN (8-205): 6.26e-49: 188: 29.35
+	Hs
		925736 RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51		AGAP1_HUMAN (2-223): 4.13e-57: 211: 32.89
+	Hs
		925423 RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51		HACE1_HUMAN (134-500): 3.45e-54: 203: 15.80
+	Hs
		925551 RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51		AGAP2_HUMAN (2-223): 3.67e-52: 198: 32.00
+	Hs
		925478 RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51		ARAP2_HUMAN (7-223): 6.18e-51: 195: 27.15
+	Hs
		893947 CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78		ANK3_HUMAN (93-695): 4.85e-40: 162: 12.34
+	Hs
		925529 RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51		ARAP1_HUMAN (8-205): 6.26e-49: 188: 29.35
+	Hs
		925238 RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51		ANK3_HUMAN (93-695): 4.85e-40: 162: 12.34
+	Hs
		925204 RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51		ANK2_HUMAN (162-494): 7.25e-30: 129: 9.52