HitPredict

Interactor 1: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Interactor 2: ARL15 (Q9NXU5)
ADP-ribosylation factor-like protein 15 (ADP-ribosylation factor-related protein 2) (ARF-related protein 2)
Gene: ARL15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arf~PH
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 779 Hs			1 204
+	Hs
		574749 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARF4_HUMAN (16-197): 2.05e-72: 218: 28.02
+	Hs
		913111 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARF6_HUMAN (29-196): 9.49e-72: 216: 33.33
+	Hs
		897405 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARF3_HUMAN (29-198): 1.76e-65: 201: 33.53
+	Hs
		918949 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB1A_HUMAN (26-198): 3.57e-65: 201: 19.10
+	Hs
		1328144 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB1B_HUMAN (26-198): 1.15e-64: 199: 17.98
+	Hs
		950560 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARF1_HUMAN (29-198): 1.2e-64: 199: 32.94
+	Hs
		950712 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARF5_HUMAN (16-197): 9.68e-65: 199: 29.12
+	Hs
		895273 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB2A_HUMAN (33-202): 4.43e-62: 193: 21.14
+	Hs
		734488 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARL2_HUMAN (32-191): 1.25e-25: 99.4: 34.73
+	Hs
		912962 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		ARF6_HUMAN (29-196): 9.49e-72: 216: 33.33
+	Hs
		912879 TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28		ARF6_HUMAN (29-196): 9.49e-72: 216: 33.33
+	Hs
		912946 RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18		ARF6_HUMAN (29-196): 9.49e-72: 216: 33.33
+	Hs
		897369 RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18		ARF3_HUMAN (29-198): 1.76e-65: 201: 33.53
+	Hs
		912911 ACAP2_HUMAN (28-517): 6.24e-39: 156: 13.10		ARF6_HUMAN (29-196): 9.49e-72: 216: 33.33
+	Hs
		950502 RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18		ARF1_HUMAN (29-198): 1.2e-64: 199: 32.94
+	Hs
		950634 RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18		ARF5_HUMAN (16-197): 9.68e-65: 199: 29.12
+	Hs
		895058 TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28		RAB2A_HUMAN (33-202): 4.43e-62: 193: 21.14
+	Hs
		895119 RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18		RAB2A_HUMAN (33-202): 4.43e-62: 193: 21.14
+	Mm
		950587 RHG21_MOUSE (22-626): 1.41e-38: 157: 14.13		ARF1_MOUSE (29-198): 1.2e-64: 199: 32.94
+	Hs
		950539 PKHA8_HUMAN (57-356): 1.52e-38: 152: 14.89		ARF1_HUMAN (29-198): 1.2e-64: 199: 32.94