HitPredict

Interactor 1: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Interactor 2: STK26 (Q9P289)
Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK)
Gene: STK26

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 779 Hs			1 416
+	Hs
		1331766 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		STK24_HUMAN (17-411): 1.47e-137: 402: 70.69
+	Hs
		682210 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		AKT2_HUMAN (2-344): 2.91e-133: 393: 25.07
+	Hs
		131607 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		STK25_HUMAN (14-411): 7.15e-134: 392: 68.63
+	Hs
		682023 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		AKT1_HUMAN (7-344): 6.09e-132: 389: 25.65
+	Hs
		568795 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		KAPCA_HUMAN (22-326): 1.68e-130: 381: 25.56
+	Hs
		610780 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		KAPCB_HUMAN (15-324): 8.54e-131: 381: 24.69
+	Hs
		1023113 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		STK4_HUMAN (4-394): 3.51e-128: 380: 41.06
+	Hs
		1027433 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		STK3_HUMAN (20-382): 2.14e-127: 378: 45.28
+	Hs
		1026227 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		PAK1_HUMAN (16-299): 6.42e-121: 363: 44.41
+	Hs
		850712 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		KS6A3_HUMAN (1-289): 3.23e-100: 315: 27.58
+	Hs
		1331724 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		M4K5_HUMAN (19-337): 9.12e-78: 259: 41.12
+	Hs
		1331590 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		TNIK_HUMAN (17-304): 2.35e-72: 248: 44.41
+	Hs
		681831 GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92		AKT1_HUMAN (7-344): 6.09e-132: 389: 25.65
+	Hs
		568704 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		KAPCA_HUMAN (22-326): 1.68e-130: 381: 25.56
+	Rn
		1144020 CAPS1_RAT (11-428): 1.59e-46: 181: 10.23		AKT3_RAT (15-340): 8.09e-132: 389: 26.05
+	Hs
		1023089 CNKR1_HUMAN (17-260): 6.93e-38: 153: 22.84		STK4_HUMAN (4-394): 3.51e-128: 380: 41.06
+	Mm
		949351 CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40		TNIK_MOUSE (17-304): 1.33e-72: 249: 44.41
+	Hs
		1263851 CNKR2_HUMAN (1-468): 1.39e-46: 181: 13.77		TNIK_HUMAN (17-304): 2.35e-72: 248: 44.41
+	Mm
		949314 RHG21_MOUSE (22-626): 1.41e-38: 157: 14.13		TNIK_MOUSE (17-304): 1.33e-72: 249: 44.41
+	Mm
		93677 E9Q6H8_MOUSE (2-527): 2.62e-38: 156: 19.44		TNIK_MOUSE (17-304): 1.33e-72: 249: 44.41