HitPredict

Interactor 1: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 779 Hs			1 7388
+	Hs
		885313 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		1068666 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		551837 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		513893 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		DMD_HUMAN (239-1700): 1.65e-14: 84.4: 8.22
+	Hs
		974145 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		963417 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Hs
		809171 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		UTRN_HUMAN (428-1437): 8.81e-11: 71.9: 13.98
+	Hs
		1059270 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		GOGB1_HUMAN (6684-7219): 2.29e-10: 70.5: 9.23
+	Hs
		521613 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		1045520 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Hs
		551692 GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		551742 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		57984 A2RRN7_HUMAN (57-428): 4.21e-47: 181: 12.44		ACTN3_HUMAN (5633-6111): 4.77e-17: 92.1: 12.20
+	Hs
		993303 CAPS1_HUMAN (11-428): 3.69e-46: 180: 11.26		ACTN3_HUMAN (5633-6111): 4.77e-17: 92.1: 12.20
+	Hs
		521561 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		513853 TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28		DMD_HUMAN (239-1700): 1.65e-14: 84.4: 8.22
+	Mm
		1143715 CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40		SPTB2_MOUSE (6378-7134): 3.94e-11: 72.8: 13.67
+	Mm
		1148443 CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40		Q68FG2_MOUSE (330-850): 2.48e-10: 70.5: 12.57
+	Mm
		561168 CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40		SPTN1_MOUSE (433-1344): 2.66e-09: 66.8: 14.03
+	Mm
		82769 CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40		B9EKJ1_MOUSE (433-1344): 4.47e-09: 66.1: 13.69