HitPredict

Interactor 1: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Interactor 2: PKHA6 (Q9Y2H5)
Pleckstrin homology domain-containing family A member 6 (PH domain-containing family A member 6) (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3)
Gene: PLEKHA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PH
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 779 Hs			1 1048
+	Hs
		1331328 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		PKHA5_HUMAN (1-1012): 2.52e-108: 365: 29.73
+	Hs
		1154076 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		NIPBL_HUMAN (150-1025): 1.8e-90: 321: 11.81
+	Hs
		1153383 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		PKHA7_HUMAN (1-953): 1.72e-90: 315: 23.76
+	Hs
		1127532 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		DOC11_HUMAN (47-721): 9.06e-68: 251: 9.76
+	Hs
		1317683 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		DOCK9_HUMAN (34-738): 2.37e-65: 244: 11.50
+	Hs
		1331278 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		PKHA4_HUMAN (7-356): 9.25e-41: 164: 26.52
+	Hs
		1331332 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		PKHA1_HUMAN (47-251): 1.94e-34: 138: 26.24
+	Hs
		1153251 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		PKHA7_HUMAN (1-953): 1.72e-90: 315: 23.76
+	Hs
		1022406 TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28		PKHA7_HUMAN (1-953): 1.72e-90: 315: 23.76
+	Hs
		1153259 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		MPRIP_HUMAN (2-667): 4.03e-48: 188: 13.90
+	Hs
		596400 GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92		RASA1_HUMAN (76-636): 1.95e-46: 183: 12.80
+	Hs
		1167372 MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57		MPRIP_HUMAN (2-667): 4.03e-48: 188: 13.90
+	Hs
		596355 RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32		RASA1_HUMAN (76-636): 1.95e-46: 183: 12.80
+	Rn
		1378274 CNKR2_RAT (1-468): 2.97e-47: 183: 14.20		CNKR2_RAT (28-466): 2.71e-43: 173: 14.55
+	Hs
		596403 RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32		ACAP2_HUMAN (32-407): 1.07e-46: 182: 14.56
+	Hs
		1035371 GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92		GAB1_HUMAN (57-571): 1.19e-38: 156: 13.15
+	Hs
		1331226 OSBL3_HUMAN (52-563): 4.71e-44: 173: 11.36		PKHA4_HUMAN (7-356): 9.25e-41: 164: 26.52