HitPredict

Interactor 1: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Interactor 2: STRAP (Q9Y3F4)
Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD)
Gene: STRAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 779 Hs			1 350
+	Hs
		1331436 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		NLE1_HUMAN (126-349): 2.92e-48: 170: 16.42
+	Hs
		793030 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		LIS1_HUMAN (181-350): 5.35e-43: 155: 13.87
+	Hs
		1288303 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		903516 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		197087 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47
+	Hs
		1318178 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		TBL1R_HUMAN (260-350): 1.48e-12: 70.4: 15.46
+	Hs
		1309164 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		TBL1Y_HUMAN (260-350): 2.01e-12: 70: 15.46
+	Hs
		1032155 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		EIF3I_HUMAN (13-127): 7.75e-09: 58.4: 20.77
+	Hs
		1153471 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		STRAP_HUMAN (1-350): 2.21e-84: 261: 100.00
+	Hs
		1153322 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		FBXW7_HUMAN (209-344): 2.04e-24: 106: 15.94
+	Hs
		1167395 MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57		FBXW7_HUMAN (209-344): 2.04e-24: 106: 15.94
+	Hs
		903302 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		1148943 CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81		FBXW7_HUMAN (209-344): 2.04e-24: 106: 15.94
+	Hs
		1153371 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		TBL1R_HUMAN (260-350): 1.48e-12: 70.4: 15.46
+	Hs
		1032108 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		EIF3I_HUMAN (13-127): 7.75e-09: 58.4: 20.77
+	Hs
		1240465 PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61		POC1A_HUMAN (1-89): 2.45e-18: 87.4: 20.23