HitPredict

Interactor 1: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Interactor 2: WIPI4 (Q9Y484)
WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45)
Gene: WDR45

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032266 - phosphatidylinositol-3-phosphate binding GO:0080025 - phosphatidylinositol-3,5-bisphosphate binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 779 Hs			1 360
+	Hs
		1288303 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		SNR40_HUMAN (34-350): 4.18e-58: 193: 12.65
+	Hs
		1326480 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		SKI8_HUMAN (117-274): 6.83e-36: 134: 20.89
+	Hs
		267793 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		TAF5L_HUMAN (108-357): 1.84e-28: 118: 12.50
+	Hs
		1313650 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		KTNB1_HUMAN (58-269): 1.58e-15: 79.8: 19.01
+	Hs
		1318178 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		TBL1R_HUMAN (187-340): 1.9e-15: 79.2: 13.19
+	Hs
		929660 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RACK1_HUMAN (7-267): 3.98e-15: 77.1: 13.01
+	Hs
		903516 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		WDR5_HUMAN (3-126): 1.37e-11: 66.8: 10.69
+	Hs
		1309164 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		TBL1Y_HUMAN (230-336): 2.34e-10: 63.7: 17.29
+	Hs
		1331436 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		NLE1_HUMAN (5-78): 5.28e-09: 59.5: 8.00
+	Hs
		1129402 PKHA1_HUMAN (16-261): 3.76e-39: 151: 16.92		WIPI3_HUMAN (14-358): 2.89e-78: 245: 47.83
+	Hs
		1153322 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		FBXW7_HUMAN (5-260): 5.89e-40: 151: 16.35
+	Hs
		1167395 MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57		FBXW7_HUMAN (5-260): 5.89e-40: 151: 16.35
+	Hs
		1148943 CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81		FBXW7_HUMAN (5-260): 5.89e-40: 151: 16.35
+	Hs
		1153371 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		TBL1R_HUMAN (187-340): 1.9e-15: 79.2: 13.19
+	Hs
		1240465 PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61		POC1A_HUMAN (3-172): 1.32e-28: 116: 10.92
+	Hs
		903302 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		WDR5_HUMAN (3-126): 1.37e-11: 66.8: 10.69
+	Hs
		596391 RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32		RACK1_HUMAN (7-267): 3.98e-15: 77.1: 13.01