HitPredict

Interactor 1: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Interactor 2: SRPRB (Q9Y5M8)
Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1)
Gene: SRPRB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 779 Hs			1 271
+	Hs
		950712 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARF5_HUMAN (46-240): 5.42e-75: 227: 21.03
+	Hs
		913111 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		918949 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		RAB1A_HUMAN (54-265): 1.14e-63: 200: 14.49
+	Hs
		574749 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARF4_HUMAN (46-240): 2.72e-63: 198: 20.51
+	Hs
		897405 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARF3_HUMAN (46-240): 1.64e-62: 196: 22.05
+	Hs
		950560 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		ARF1_HUMAN (46-240): 2.73e-62: 195: 21.54
+	Hs
		1331381 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		SAR1A_HUMAN (62-195): 1.47e-11: 64: 24.63
+	Hs
		912962 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		950634 RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18		ARF5_HUMAN (46-240): 5.42e-75: 227: 21.03
+	Hs
		912879 TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		912946 RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		912911 ACAP2_HUMAN (28-517): 6.24e-39: 156: 13.10		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		897369 RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18		ARF3_HUMAN (46-240): 1.64e-62: 196: 22.05
+	Hs
		950502 RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18		ARF1_HUMAN (46-240): 2.73e-62: 195: 21.54
+	Hs
		913123 PKHA1_HUMAN (16-261): 3.76e-39: 151: 16.92		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		913121 PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Mm
		950587 RHG21_MOUSE (22-626): 1.41e-38: 157: 14.13		ARF1_MOUSE (46-240): 2.73e-62: 195: 21.54
+	Hs
		950539 PKHA8_HUMAN (57-356): 1.52e-38: 152: 14.89		ARF1_HUMAN (46-240): 2.73e-62: 195: 21.54
+	Hs
		913206 FARP1_HUMAN (6-167): 1.07e-24: 112: 17.96		ARF6_HUMAN (60-239): 5.9e-70: 215: 20.00
+	Hs
		881505 GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92		ARL4C_HUMAN (67-197): 1.37e-11: 64: 25.56