HitPredict

Interactor 1: EHD1 (Q9H4M9)
EH domain-containing protein 1 (PAST homolog 1) (hPAST1) (Testilin)
Gene: EHD1

Interactor 2: EPN1 (Q9Y6I3)
Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1)
Gene: EPN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21115825
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 534 Hs			1 576
+	Mm
		1194352 EHD1_MOUSE (1-534): 0: 823: 99.44		EPN1_MOUSE (1-576): 1.93e-88: 286: 94.44
+	Hs
		1349324 EHD2_HUMAN (1-534): 0: 776: 70.50		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Mm
		1194350 EHD2_MOUSE (1-534): 0: 777: 70.87		EPN1_MOUSE (1-576): 1.93e-88: 286: 94.44
+	Hs
		1328938 EHD1_HUMAN (1-534): 0: 822: 100.00		EPN3_HUMAN (1-571): 3.16e-55: 199: 40.16
+	Ce
		1259347 Q8WSP1_CAEEL (1-534): 0: 777: 66.85		Q9BI72_CAEEL (1-477): 2.39e-73: 243: 32.72
+	Mm
		1265097 EHD1_MOUSE (1-534): 0: 823: 99.44		EPN3_MOUSE (1-571): 2.38e-50: 185: 37.05
+	Hs
		1328941 EHD2_HUMAN (1-534): 0: 776: 70.50		EPN3_HUMAN (1-571): 3.16e-55: 199: 40.16
+	Mm
		1206518 EHD2_MOUSE (1-534): 0: 777: 70.87		EPN3_MOUSE (1-571): 2.38e-50: 185: 37.05
+	Hs
		1244792 REPS2_HUMAN (315-527): 1.56e-47: 177: 22.79		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Hs
		1057081 REPS1_HUMAN (372-527): 2e-35: 143: 28.66		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Mm
		1194353 ITSN1_MOUSE (426-527): 9.71e-29: 123: 38.24		EPN1_MOUSE (1-576): 1.93e-88: 286: 94.44
+	Hs
		1223707 REPS1_HUMAN (372-527): 2e-35: 143: 28.66		ENTD1_HUMAN (5-293): 2.05e-79: 263: 37.42
+	Hs
		787913 EPS15_HUMAN (446-528): 4.73e-13: 73.9: 34.52		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Hs
		787997 EPS15_HUMAN (446-528): 4.73e-13: 73.9: 34.52		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Hs
		307533 ITSN1_HUMAN (426-527): 3.14e-29: 125: 37.26		EPN2_HUMAN (1-566): 6.51e-54: 195: 38.02
+	Sc
		692257 PAN1_YEAST (332-521): 4.24e-20: 96.7: 21.47		ENT1_YEAST (3-228): 6.81e-62: 212: 36.73
+	Sc
		692249 PAN1_YEAST (332-521): 4.24e-20: 96.7: 21.47		ENT2_YEAST (3-538): 7.67e-59: 208: 19.59
+	Dm
		91160 E3CTP7_DROME (434-531): 2.68e-17: 87.3: 34.00		Q7KU90_DROME (1-571): 4.4e-58: 209: 31.51
+	Hs
		787969 EPS15_HUMAN (446-528): 4.73e-13: 73.9: 34.52		EPN3_HUMAN (1-571): 3.16e-55: 199: 40.16
+	Hs
		203228 ITSN1_HUMAN (426-527): 3.14e-29: 125: 37.26		SYNJ1_HUMAN (246-573): 8.14e-20: 96.3: 14.11