HitPredict

Interactor 1: RNF41 (Q9H4P4)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Interactor 2: RNF41 (Q9H4P4)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.923

The method score is based on:

Property Details
Experiments 25416956, 28542518, 29560723, 22493164, 31515488
Identification Methods two hybrid, fluorescent resonance energy transfer, proximity labelling technology, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains USP8_interact~USP8_interact, zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005128 - erythropoietin receptor binding
GO:0005135 - interleukin-3 receptor binding
GO:0005829 - cytosol
and 22 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 317
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024