HitPredict

Interactor 1: RNF41 (Q9H4P4)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31067453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008270 - zinc ion binding GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 956
+	Hs
		585077 RO52_HUMAN (3-295): 1.95e-61: 204: 16.94		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1343408 TRAF6_HUMAN (2-118): 1.24e-29: 119: 34.75		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1024766 TRAF3_HUMAN (6-132): 1.42e-28: 117: 25.78		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1163039 TRAF7_HUMAN (8-137): 1.59e-23: 102: 21.77		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1283425 RN166_HUMAN (9-118): 8.54e-24: 99.1: 23.42		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Mm
		936243 TRAF6_MOUSE (2-132): 5.24e-30: 121: 34.85		CYLD_MOUSE (1-956): 0: 1825: 94.46
+	Mm
		1141415 TRAF3_MOUSE (6-132): 9.1e-28: 114: 24.62		CYLD_MOUSE (1-956): 0: 1825: 94.46
+	Hs
		1343411 RN114_HUMAN (16-107): 5.06e-09: 57.8: 31.18		CYLD_HUMAN (1-956): 0: 1872: 100.00