HitPredict

Interactor 1: RNF41 (Q9H4P4)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Interactor 2: UBP25 (Q9UHP3)
Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25)
Gene: USP25

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 1055
+	Hs
		1355521 TRIM1_HUMAN (2-299): 7.77e-40: 150: 16.57		UBP25_HUMAN (1-1055): 0: 1021: 100.00
+	Hs
		800627 TRIM5_HUMAN (11-298): 1.5e-56: 192: 19.19		UBP5_HUMAN (148-656): 1.28e-85: 297: 15.09
+	Hs
		800578 TRI26_HUMAN (3-301): 1.09e-51: 180: 12.62		UBP5_HUMAN (148-656): 1.28e-85: 297: 15.09
+	Hs
		800631 TRI39_HUMAN (9-271): 2.23e-49: 173: 16.54		UBP5_HUMAN (148-656): 1.28e-85: 297: 15.09
+	Hs
		1136214 RC3H1_HUMAN (14-317): 1.43e-39: 150: 16.17		USP9X_HUMAN (142-459): 2.23e-67: 250: 20.22
+	Hs
		1295898 TRI31_HUMAN (3-275): 1.27e-40: 148: 17.69		UBP47_HUMAN (163-418): 1.83e-39: 161: 18.45
+	Hs
		271032 RO52_HUMAN (3-295): 1.95e-61: 204: 16.94		UBP2_HUMAN (514-660): 9.45e-16: 83.8: 17.69
+	Hs
		1273788 TRI11_HUMAN (3-295): 1.14e-56: 191: 13.92		UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78
+	Hs
		271189 TRIM5_HUMAN (11-298): 1.5e-56: 192: 19.19		UBP2_HUMAN (514-660): 9.45e-16: 83.8: 17.69
+	Hs
		1223388 TRI22_HUMAN (3-300): 1.61e-53: 184: 17.21		UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78
+	Hs
		536961 TRI27_HUMAN (3-275): 1.78e-47: 168: 14.75		UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78
+	Hs
		271195 TRI39_HUMAN (9-271): 2.23e-49: 173: 16.54		UBP2_HUMAN (514-660): 9.45e-16: 83.8: 17.69
+	Hs
		271027 TRI27_HUMAN (3-275): 1.78e-47: 168: 14.75		UBP2_HUMAN (514-660): 9.45e-16: 83.8: 17.69
+	Hs
		1019375 TRI26_HUMAN (3-301): 1.09e-51: 180: 12.62		UBP36_HUMAN (560-684): 1.95e-11: 70.7: 22.84
+	Hs
		271184 TRI34_HUMAN (5-298): 1.44e-43: 157: 17.43		UBP2_HUMAN (514-660): 9.45e-16: 83.8: 17.69
+	Hs
		1273857 TRI31_HUMAN (3-275): 1.27e-40: 148: 17.69		UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78
+	Hs
		271214 TRIM1_HUMAN (2-299): 7.77e-40: 150: 16.57		UBP2_HUMAN (514-660): 9.45e-16: 83.8: 17.69
+	Hs
		1273839 TRAF4_HUMAN (2-132): 2.42e-31: 124: 30.30		UBP7_HUMAN (547-758): 1.65e-17: 90.2: 21.78
+	Hs
		271136 TRI50_HUMAN (3-208): 1.87e-33: 129: 16.27		UBP2_HUMAN (514-660): 9.45e-16: 83.8: 17.69
+	Hs
		271142 LNX2_HUMAN (8-122): 2.47e-30: 122: 28.45		UBP2_HUMAN (514-660): 9.45e-16: 83.8: 17.69