Interactor 1: COE3 (Q9H4W6)
Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF-like 2) (O/E-2) (OE-2)
Gene: EBF3

Interactor 2: COE2 (Q9HAK2)
Transcription factor COE2 (Early B-cell factor 2) (EBF-2)
Gene: EBF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 32296183, 33961781, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains COE1_DBD~COE1_DBD, COE1_DBD~TIG, COE1_HLH~COE1_HLH, COE1_HLH~TIG, TIG~TIG
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 596
Hs

1 575
+ Hs
+ Mm
+ Mm
+ Ce

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Last updated: 15 Jul 2024